The letters in the logo represent "Clinical Trials Transformation Initiative," but they have been rearranged like puzzle pieces coming together. This arrangement makes more efficient use of space, representing the efficiencies that CTTI is seeking for clinical trials. The overt message of the logo is that change is imminent and once the pieces come together, a dramatic transformation will occur.

The lower "T" in the logo is a mirror image of the upper "T" and highlighted with color. This "T" stands for transformation.  The color highlight emphasizes that change is coming. The position of the T conveys transformation in a powerful and positive way.